Purple hand syndrome phenytoin

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August undefined, 2024

WebThe patient’s right hand was cool with a purple mottling spreading from the IV site. Her attending physician was notified, and warm compresses with elevation were applied to … WebSep 1, 2024 · Purple glove syndrome (PGS) is an atypical adverse drug reaction that can occur after the administration of intravenous phenytoin. Although definitions of PGS vary, …

Warfarin and phenytoin drug interaction with possible purple glove syndrome

WebOct 1, 1998 · Objective: To determine the incidence, risk factors, and long-term sequelae of the purple glove syndrome (PGS) in hospital patients receiving IV phenytoin. Background: … WebJan 1, 2024 · Purple Glove Syndrome (PGS) is a rare complication of intravenous phenytoin administration which is illustrated by delayed soft tissue injury of the skin conterminous … up board topper list

Purple glove syndrome: a complication of intravenous phenytoin

WebJul 2, 2015 · In her 1992 publication, Hanna named a delayed, soft tissue injury of the hand and forearm following IV administration of phenytoin “purple glove syndrome” (PGS) [4, 5]. Increasing reports of this condition have recently emerged, some involving permanent tissue damage or loss, leading to questions regarding the safety and risk-benefit profile of IV … WebNote, phenytoin sodium is highly alkaline and irritant, and may result in “purple glove syndrome” (progressive distal limb oedema, discolouration, pain which in severe cases may involve extensive skin necrosis and limb ischaemia) if administered via peripheral line. 2. Ensure adequate facilities are available to institute recommended monitoring WebJan 1, 2024 · Acral manifestations of systemic diseases: drug induced Purple glove syndrome. Phenytoin has been used for the treatment of seizures since 1956. It is administered intravenously in emergency departments and hospitals to patients with isolated seizures or undergoing neurosurgical procedures, who are unable to receive oral … recreation hamilton near me

A Rare Complication of Phenytoin Infusion in Newborn: Purple Glove Syndrome

Trimethoprim-Sulfamethoxazole–Induced Rhabdomyolysis; …

WebKeywords: Amputation, general anaesthesia, phenytoin, purple glove syndrome. INTRODUCTION. Intravenous (IV) administration of phenytoin can result in soft tissue injury at the site of injection leading to oedema and purplish-black discolouration of the hand. This is known as the purple glove syndrome (PGS). WebA severely handicapped boy had been treated with phenytoin and his seizures were controlled well. At 10 years of age, a pharmacy gave about 1000 mg of phenytoin instead … up board update recreation hamilton login

"WebPurple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that typically presents with pain, edema, and discoloration at the injection site that spreads to … " - Purple hand syndrome phenytoin

Purple hand syndrome phenytoin

Warfarin and phenytoin drug interaction with possible purple glove ...

WebThe purple-blue discoloration and edema of the right hand and arm. Purple Glove syndrome is a rare complication of intravenous phenytoin infusion. The incidence ranges from 1.7% … WebKeywords: Amputation, general anaesthesia, phenytoin, purple glove syndrome. INTRODUCTION. Intravenous (IV) administration of phenytoin can result in soft tissue …

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WebThere are several possible explanations for the development of purple glove syndrome. First, sodium hydroxide, propylene glycol, and ethanol are added to the phenytoin solution to raise the pH ... Purple glove syndrome (PGS) is a poorly understood skin disease in which the extremities become swollen, discoloured and painful. PGS is potentially serious, and may require amputation. PGS is most common among elderly patients and those receiving multiple large intravenous doses of the epilepsy drug phenytoin. Compartment syndrome is a complication of PGS.

WebSep 1, 2024 · Purple glove syndrome (PGS) is an atypical adverse drug reaction that can occur after the administration of intravenous phenytoin. Although definitions of PGS vary, it has been loosely defined as signs and symptoms of progressive edema, discoloration, and pain that occurs following administration of intravenous phenytoin [1] . WebSep 11, 2012 · Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that typically presents with pain, edema, and discoloration at the injection site that spreads to the distal limb.

WebJul 1, 2010 · A 60-year-old woman was admitted in a peripheral hospital for frontal bone fracture following road traffic accident (RTA) with normal brain parenchyma and generalized tonic-clonic seizure, for which she received 900 mg of loading dose of phenytoin dissolved in 100 ml of normal saline through a 22-gauge peripheral intravenous catheter kept in her … WebNov 23, 2024 · Raynaud's (ray-NOSE) disease causes some areas of the body — such as fingers and toes — to feel numb and cold in response to cold temperatures or stress. In Raynaud's disease, smaller arteries that supply blood to the skin narrow. This limits blood flow to affected areas, which is called vasospasm. Raynaud's phenomenon. Raynaud …

WebIntravenous phenytoin, available for use since 1956, has several well known adverse effects, such as hypotension, arrhythmias and toxicity. Purple glove syndrome is a less common …

WebDec 1, 1992 · Medicine. Journal of Neuroscience Nursing. &NA; Intravenous phenytoin, available for use since 1956, has several well known adverse effects, such as … recreation hamilton.caWebSep 16, 2015 · The authors point out that purple glove syndrome is a rare condition that almost always occurs after intravenous administration of phenytoin. The purple discoloration typically occurs distal to the site of intravenous phenytoin administration. What makes this case unique is that it occurred after 20 days of oral therapy in a patient … recreation hall penn statehttp://patientsafety.pa.gov/ADVISORIES/Pages/200612_12.aspx recreation hallWebApr 1, 2016 · Compartment syndrome is a rare complication of spectrum of purple glove syndrome, seen as a side effect of intravenous phenytoin. This involves rapid discolouration of the involved limb along with ... recreation hamilton swimmingWebJun 28, 2024 · PGS is a rare serious adverse reaction to intravenous phenytoin. Its incidence ranges from 1.5 to 5.9% [ 1 ]. Its manifestation includes pain, skin discolouration, blister formation, sloughing, ulceration, and necrosis. Usually clinical manifestations are limited to the superior limbs but there are descriptions of cases with involvement of ... recreation hamptonWebSep 15, 2024 · Intravenous phenytoin administration may rarely be complicated by the Purple Glove Syndrome. The basic pharmacology, presentation, and management of … recreation hamiltonWebPhenytoin. Purple glove syndrome: 2 case reports. Reactions Weekly volume 1788, ... In a case series, two women (an 81-year-old woman and an 87-year-old woman) were … recreation hampton gym