Lamp2a是什么
TīmeklisAnti-LAMP2A antibody [EPR4207 (2)] - Lysosome Marker (ab125068) Research with confidence – consistent and reproducible results with every batch Long-term and scalable supply – powered by … TīmeklisLAMP2a degrades PRDX1 (peroxiredoxin 1) and CRTC1 (CREB-regulated transcription coactivator 1) to promote macrophage pro-tumorigenic activation. Interpretation: Our study suggests that tumor cells utilize LAMP2a-PRDX1/CRTC1 axis to modulate TAMs activation and promote tumor growth, reveals the role of LAMP2a in macrophage …
Lamp2a是什么
Did you know?
Tīmeklislamp2a细胞显示出与对照d3细胞不同的基因表达谱，而lamp2a /dm-αkg细胞显示出与对照d3细胞相似的基因表达谱（图5g）。 基因集富集分析证实，LAMP2A过表达后，与干细胞维持相关的基因被下调，而与干细胞分化相关的基因被上调。 TīmeklisCMA is a selective autophagic process that depends on LAMP2A (lysosomal-associated membrane protein 2A), a mammal and bird-specific membrane glycoprotein that translocates cytosolic proteins containing a KFERQ-like peptide motif across the lysosomal membrane.
Tīmeklis2024. gada 7. nov. · LAMP2A possesses a highly glycosylated luminal region that is common to all LAMP2 isoforms and a specific 11-amino-acid-long cytosolic C-terminal tail . By virtue of this particularity, LAMP2A (but neither of the 2 other isoforms, LAMP2B and LAMP2C), participates in CMA, which facilitates selective import and …
Lysosome-associated membrane protein 2 (LAMP2), also known as CD107b (Cluster of Differentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins. The protein encoded by this gene is a member of a family of membrane glycoproteins. This … Skatīt vairāk The gene for LAMP2 has 9 coding exons and 2 alternate last exons, 9a and 9b. When the last exon is spliced with the alternative exon, it is a variant called LAMP2b, which varies in the last 11 amino acids of its C … Skatīt vairāk Lysosomes are cell organelles found in most animal cells. Their main functions center around breaking down materials and debris in the … Skatīt vairāk • CA77.1 • QX39 Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and Homeostatic Agents. 16 (2): 147–51. PMID 12144129. • Schleutker J, Haataja L, Renlund M, Puhakka L, Viitala J, Peltonen L, … Skatīt vairāk LAMP2 has been specifically implicated in tumor cell metastasis. Both LAMP1 and LAMP2 have been found expressed on the surface of cancerous tumors, specifically in cells of highly metastatic cancer such as colon cancer and melanoma. They are rarely found on … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • LAMP2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an overview of all the structure information … Skatīt vairāk TīmeklisLAMP分别代表什么？ · L代表服务器操作系统使用Linux · A代表网站服务使用的是Apache软件基金会中的httpd的软件 · M代表网站后台使用的数据库时MySQL数据库 · P代表网站是使用PHP/Perl/Python等语言 …
TīmeklisCritically, Lamp2a is required for HCC xenograft growth in vivo by helping cells to avoid apoptosis and promoting cell proliferation. Furthermore, a significant correlation between Lamp2a expression and tumor size or cumulative recurrence was uncovered in HCC patients. Collectively, the present study shows that impaired Lamp2a expression in …
Tīmeklis2024. gada 24. apr. · 这些作者表示，人们在一生中产生相同数量的lamp2a受体，不过，这些受体随着年龄的增加而退化得更快，因此老年人往往有较少的受体用于将不需要 ... film 2 h 37 streamingTīmeklis2024. gada 22. sept. · LAMP2A and HSC70 are crucial players in chaperone-mediated autophagy (CMA), a targeted, lysosome-dependent protein degradation pathway. Elevated LAMP2A levels, indicative of increased CMA activity, are observed in several malignancies, and CMA downregulation may be exploited therapeutically. We … film2downloadTīmeklisLamp2a is released from the membrane by the action of these proteases, and then the truncated lamp2a is rapidly degraded within the lysosomal matrix. Membrane degradation of lamp2a is a regulated process that is inhibited in the presence of substrates for chaperone-mediated autophagy and under conditions that activate that … ground service reservoirTīmeklisLAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins. LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome. film 2 hearts streaming vfTīmeklisLAMP2 lysosomal associated membrane protein 2 [ (human)] Gene ID: 3920, updated on 7-Feb-2024 Summary The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. ground services international incTīmeklisLAMP2a Rabbit Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。 Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。 film 2getherTīmeklisLAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins. LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome. ground service msfs 2020