WebMay 31, 2024 · So definitely a strong anti-resorptive type of medication such as Reclast is usually recommended to combat the dramatic increase of bone resorption after Prolia. I think some have transitioned to an oral bisphosphonate, but which transition medication is best is probably yet to be determined. WebAnd here's the icing on the cake: the same Harvard Medical School study mentioned before reports that bone loss (resorption) gradually resumes after stopping the drugs, and achieves normal (pre-menopausal) levels in approximately five years. You see, the major osteoporosis and osteopenia drugs close the door on new bone formation, leaving only ...
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WebNov 22, 2024 · Prolia works by blocking a protein called RANK (receptor activator of nuclear factor kappa beta) and helps prevent bone cells called osteoclasts from breaking down … WebMar 7, 2024 · it is important to follow up with another medication (reclast or oral bisphosphanate) for 18-30 months after stopping prolia. you will still lose some of the gains made while on prolia but not all by doing that. its also been shown to prevent multiple vertebrae fractures. best wishes Brydy. Reply Share React Ladybug-88 Mar 9, 2024 • 5:15 … software ndhu
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WebJul 10, 2024 · To reduce the risk of these rare complications, your doctor may recommend that you temporarily stop taking bisphosphonates after 3 to 5 years. This is sometimes called a bisphosphonate holiday. People who have severe osteoporosis may need to wait for 10 years before they stop taking these drugs. WebOct 29, 2024 · Symptoms of ONJ can range from very mild to severe. ONJ looks like an area of exposed bone in your mouth. It can cause tooth or jaw pain and swelling in your jaw. … WebProlia stops RANKL from binding to its receptor RANK so reduces the development of new osteoclasts and reduces bone breakdown, bone loss, bone pain, and other bone … software nd filter